glp 1 menopause symptoms Let's talk about GLP-1 medications in the context of perimenopause and menopause, because this is where the conversation most often gets flattened into something it is not. This is not about vanity GLP‑1 and Menopause: Mounjaro, Wegovy,

But individual response varies

Study designs to investigate causality rigorously Prospective new-user cohort with active comparator + Recruit new semaglutide users and matched new users of a comparator second-line diabetes therapy with lower genital infection confounding (e.g., DPP4 inhibitor), stratified by menopausal status and baseline GSM

Patients should never discontinue semaglutide without medical guidance, as abrupt cessation can lead to worsening glycemic control

The trial also featured a "novel, patient-centric approach to clinical trial design." Placebo participants who regained 50% or more of their weight were eligible for rescue therapy with orforglipron