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It was only during the clinical trials for FDA approval that researchers and drug designers realized that patients were simultaneously losing weight in some cases, a lot of it

Whether you inject in the abdomen, thigh, or arm, you should notice appetite suppression starting within the first week and meaningful weight loss within the first month

Pandey S, Mangmool S, Madreiter-Sokolowski CT, Wichaiyo S, Luangmonkong T, Parichatikanond W (2023) Exendin-4 protects against high glucose-induced mitochondrial dysfunction and oxidative stress in SH-SY5Y neuroblastoma cells through GLP-1 receptor/Epac/Akt signaling

The mechanisms engaged by this peptideantibody conjugate leading to weight loss and metabolic improvement remain unclear