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The research has not yet been published in a peer-reviewed journal, and experts cautioned that the study was observational, meaning it cannot prove the drugs directly slowed cancer progression

Emotional Flattening or Reduced Pleasure Some patients report: Feeling emotionally flat Reduced excitement or pleasure Lower motivation Fatigue Feeling less emotionally engaged Researchers believe this may relate to changes in dopamine and reward signaling

More serious but less common adverse effects include pancreatitis, gallbladder disease (cholecystitis and cholelithiasis), and acute kidney injury, particularly in the setting of severe dehydration from gastrointestinal symptoms