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While it likely wont be fatal on its own, taking too much melatonin can potentially cause you to feel sleepy during unexpected and unintended times , which can be a problem if you are driving, operating heavy machinery, or otherwise in a potentially dangerous situation

Thus, whilst the capacity of GLP-1R signaling to influence the microbiome is evident, direct evidence that GLP-1RAs exert their anti-inflammatory effects in the gut via modulation of the microbiota remains to be established

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