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This early inflammation can manifest as joint stiffness, swelling, or diffuse aching as your immune system adjusts to the medication

The FDA-approved versions (Ozempic and Wegovy) carry a black-box warning about medullary thyroid carcinoma risk based on rodent studies, but this applies primarily to patients with a personal or family history of medullary thyroid cancer (MTC) or Multiple Endocrine Neoplasia type 2 (MEN2)