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Local renal autoantibody production in lupus nephritis

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pretreated rats for 13 days with candesartan (0.5 mg/kg/day) followed by 24 h of isolation in metabolic cages, and they found that candesartan blocks the stress-induced augments of CRF in the cortical and prevents benzodiazepine receptors from binding in the paraventricular nucleus and cortex (153)