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The side effects of GLP-1 RAs can include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which are usually transient but may affect patient adherence, as well as rarer complications that require careful monitoring in clinical practice

Thus, therapeutic interventions targeting neurovascular health in the context of metabolic syndrome may require a combined approach, emphasizing the pharmacological activation of GLP-1 receptors and dietary modification to achieve optimal results in treating and preventing neurodegenerative and metabolic dysfunctions

An oral glucose tolerance test (OGTT) was performed to clarify glycaemic status [17]