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NICE technology appraisal guidance (TA875) recommends semaglutide 2.4mg for adults with a BMI of 35 kg/m or greater, or 30 kg/m or greater with at least one weight-related comorbidity, when provided alongside a reduced-calorie diet and increased physical activity

L-carnitine has a central role in the metabolism of fats and so extra carnitine is often added to weight-loss diets as it helps to break down body fat while maintaining lean muscle mass

The jump from 15% to 25% weight loss transforms the clinical significance of the treatment

Reassess Your Nutrition Plateaus are often linked to unintentional calorie creep or inadequate protein