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Our previous studies showed that CoQ 10 H 2 increases cAMP and enhances the activity of SIRT1 and PGC-1, thereby improving mitochondrial function and inhibiting oxidative stress 42

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Apoptotic cells in lung tissues were evaluated through Terminal-deoxynucleoitidyl transferase mediated nick end labeling (TUNEL) staining by a Roche In Situ Cell Death Detection Kit (Roche, U.S.) according to the suggested protocols