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The lack of an increased CV risk in SUSTAIN 6 and PIONEER 6 is consistent with evidence from a meta-analysis summarizing data from SUSTAIN and PIONEER glycemic efficacy trials, which included patients with T2D at relatively low CV risk ( Cardiovascular Safety of Other GLP-1RAS To date, seven CVOTs have been conducted with GLP-1RAs ( Figure 2

Based on these results, doctors should consider whether a person has sleep apnea when deciding whether to prescribe a GLP-1 drug, researchers said

Additionally, these treatments have certain side effects

Moreover, for general glycemic control, GLP-1 RAs are now often preferred over insulin when injectable therapy is needed, unless there is severe uncontrolled hyperglycemia