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As a result, the low DGAT1 expression observed in the presence of Ex-4 is most likely a response to reduced FAs uptake rather than reduced de novo lipogenesis, ruling out a role for reduced de novo lipogenesis in the Ex-4-induced steatosis improvement

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1 The FDA reiterated that compounded drugs are not FDA-approved, meaning the agency does not review their safety, effectiveness, or quality prior to marketing