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Conclusions In summary, the results of this large active comparator, new user cohort study indicate that GLP-1 receptor agonists are not associated with an increased risk of suicidal ideation, self-harm, and suicide when compared with DPP-4 inhibitors or SGLT-2 inhibitors among patients with type 2 diabetes

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As we follow long-term outcomes of current therapies with new medications coming to market, it will be crucial to continue to evaluate lipid-specific outcomes that play a role in the overall cardiovascular benefits of GLP-1RA and other highly effective anti-obesity medications