It is the disciplined management of many small risks that compound over time: blood pressure, ApoB and LDL burden, insulin resistance, visceral fat, sleep quality, strength, hearing, vision, social connection, and inflammation
As most of the available evidence stems from in vitro and preclinical studies, there remains a need for long-term and in vivo research to substantiate these findings and assess their translational relevance
"We think that some of these people may be changing behavior, nutrition, lifestyle, [and] also may be changing the hormones in their body by being on [GLP-1 medications], changing how their brain sort of operates or functions permanently," Narula said
There were two trials for each level (57 digits)