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2 (a) central obesity assessed by waist circumference equal to or greater than 102 cm (40 inches) in men, and equal or greater than 88 cm (35 inches) in women

Using SAL1 recombinant protein treated with reduced or oxidized forms of DTT and glutathione, it appeared that Cys119 is involved in an intermolecular disulfide bridge that led to the formation of a dimeric form and that this would favor the formation of an additional intramolecular disulfide bridge between Cys167 and Cys190 (Chan et al., 2016)

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For some, obesity is primarily driven by insulin-related metabolic issues