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Robert Recker, a bone metabolism researcher at Creighton University whose work on bisphosphonate adherence has been cited in over 200 publications, has noted that "the single most modifiable predictor of bisphosphonate treatment failure is incorrect administration timing," a finding consistent with the adherence data in the POSSIBLE US observational study (N=over 15,000 osteoporosis patients)

In addition to looking at the factors that affect a persons weight trajectory, researchers tracked glycemic control in patients who had pre-diabetes at the start of the study

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