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Research published in Nutrients in 2024 examined L-carnitine's effects on body composition during caloric restriction, finding that supplementation helped preserve lean muscle mass while enhancing fat lossa critical consideration when prescribing weight loss medications (Fielding et al., 2024)
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A Phase 2 trial (a mid-stage human trial, typically involving a few hundred participants) published in the New England Journal of Medicine in 2023 reported an average weight loss of about 24% at 48 weeks with the highest dose
