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As a result, combining a GLP-1 receptor agonist with an anti-muscarinic agent may result in an additional or synergistic broncho-relaxant effects due to complementary mechanisms of action, as seen with different classes of bronchodilators administered in combination [122]

While this mechanism remains speculative, the underlying physiology of cryotherapy-induced blood flow changes supports the concept

It can be neuroprotective, cardioprotective, and counteracts the QTc prolongation induced by neuroleptics

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