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This approach can greatly inform further clinical studies and improve patient outcomes," remarked Dr Dipender Gill, Clinical Research Fellow in the Department of Epidemiology and Biostatistics at the School of Public Health of Imperial College London, a senior author of the study

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In these high-risk populations, Semaglutide reduced the risk of heart failure events and cardiovascular death, underscoring its potential in managing complex cardiometabolic conditions This protective effect is attributed to several mechanisms that promote heart health, including: Decreased inflammation Enhanced endothelial function Lowered blood pressure Decrease body weight Tirzepatide has a similar mechanism of action with added benefits due to its dual target on two receptors

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