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Genomics 24 , 701596, (2014)

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Excess Fe 2+ is oxidized to Fe 3+ by ferroportin (FPN) 24

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Specifically, the side chain of R283 6.55 moves towards F279 6.51 and H280 6.52 due to steric effects with the octanoyl chain of ghrelin or the phenyl group of ibutamoren (Fig

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This suggests that the actual prevalence of PBH might be higher than what is captured by studies that rely on self-reported symptoms or hospital records [18]

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