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Neither is universally "better" they belong to different drug classes with different mechanisms, FDA-approval scopes, and use durations

Notably, when Melanotan II-treated mice were compared to vehicle-treated pair-fed mice that lost equivalent body weight through caloric restriction, the Melanotan II group showed greater reductions in subcutaneous adipose tissue, suggesting effects beyond simple appetite suppression

acidophilus can promote the production of beneficial short-chain fatty acids such as butyrate, which supports gut lining health and efficient nutrient absorption

PubMed , International Journal of Stem Cells , vol