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the metabolically stabilized 6-AH family member, D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 had a t 6-AH family members were found to act as mimics of the dimerization domain of FIGF (hinge region), and inhibited the interaction of an HGF molecule with a 3 H-hinge region peptide resulting in an attenuated capacity of HGF to activate its receptor Met

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Commercial and Therapeutic Applications These multifaceted effects have positioned GHK-Cu as one of the most studied and commercially successful peptides in cosmetic dermatology and aesthetic medicine, with incorporation into hundreds of skincare products and professional aesthetic treatments over the past several decades