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Initially developed for managing type 2 diabetes, semaglutide has since been approved for weight loss and is now widely prescribed for both conditions

For example, improved glycemic control and weight loss achieved through Semaglutide may contribute to better overall physical health, which can positively impact mental health and potentially enhance the therapeutic effects of antidepressants

It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2

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