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Together with our findings in mice, these data suggest that p53 signalling, and possibly p53-dependent LAM recruitment to AT, may limit the effectiveness of weight loss and weight loss retention

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However, researchers also highlight limitations, including: Small study groups Differences in treatment methods Limited long-term data Variation in individual responses This means glutathione should be viewed as a treatment option that may support skin brightness rather than a guaranteed solution for everyone

[10] No head-to-head trial exists