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What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry

However, the addition of diuretic therapy has been shown to sensitize African American patients to these agents to obtain similar responses as in nonAfrican American patients

However, trouble absorbing this vitamin can occur in just about anyone