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Oxidative stress then accelerates the aggregation of -synuclein which subsequently binds and sequesters available GSH, creating a destructive feedback loop of protein misfolding and antioxidant loss (Hoepken et al., 2007)

10.1016/j.regpep.2009.11.012 95 TurkovicB.SikiricP.SeiwerthS.MiseS.AnicT.PetekM.et al (2004)

11 Second, the buffering activity of SNAC promotes enhanced solubility of semaglutide, providing higher concentrations of the drug to the gastric membrane