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GHK-Cu binds to copper and interacts with several biological pathways connected to: Collagen and elastin synthesis supporting the structural proteins responsible for skin firmness Antioxidant activity helping neutralize oxidative stress that accelerates visible aging Anti-inflammatory signaling calming irritation that can slow healing Blood vessel formation (angiogenesis) supporting nutrient delivery to healing tissue Stem cell activation encouraging the migration of skin cells involved in repair Because of these overlapping functions, researchers have studied the peptide not just for cosmetic purposes but for wound healing, post-surgical recovery, and hair follicle stimulation

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The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases