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This shift has turned GLP-1 therapy into one of the fastest-growing pharmaceutical categories in the world

In a post-hoc analysis of the published SURPASS trials, the change in systolic blood pressure was greater for tirzepatide versus the comparators of the trials (tirzepatide 5 mg: -5.1 to -1.3 mmHg, tirzepatide 10 mg: -6.5 to -1.7 mmHg, tirzepatide 15 mg: -11.5 to -3.1 mmHg) [65]

Progressive overload (gradually increasing weight or reps each week) is critical

Their current estimate for global obesity drug sales by 2030 is $105 billion, down from earlier forecasts of $130 billion, based on steeper price erosion and changing customer-use patterns