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Conjugation Glutathione-S-transferases attach glutathione to electrophilic drugs, chemical metabolites and other reactive compounds, preparing them for further processing and excretion
Unlike muscle tissue, these structures dont get the same vascular supply, making recovery much harder and often incomplete without intervention
30 SLE T cells display increased mitochondrial mass, reflecting enhanced biogenesis but insufficient mitophagy, alongside elevated IFN- signaling that further suppresses mitophagic clearance and primes dendritic cell activation
Moreover, use of glucocorticoids by IBD patients potentiates clotting propensity (Kappelman 2011)
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