In patients with mild renal impairment, as per the European labeling, dose adjustment for GLP-1 RAs is not needed, but some cannot be used or are not recommended in patients with severe renal impairment and end-stage disease [12], with exceptions such as dulaglutide, liraglutide, and semaglutide, which can be used in severe renal impairment but not end-stage renal disease
Dangers of Heavy or Regular Drinking With GLP-1 Drinking in small amounts is okay if a doctor says so, but drinking often brings more problems
Hirshberg B, Parker A, Edelberg H, Donovan M, Iqbal N
It has multiple causes , including genetics, hormones and brain chemistry, nutrition, poor sleep, other diseases (like PMOS in my case), and environmental factors, according to the Obesity Medicine Association