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In vivo animal experiments showed that daily administration of NNMTi for 28 days to dietinduced obese (DIO) mice significantly upregulated the expression of lipolysisrelated genes (such as ATGL and HSL) and downregulated lipogenesisrelated genes (such as FAS and ACC), indicating that NNMTi effectively promotes fat breakdown and inhibits fat synthesis

For those with neurological symptoms, hydroxocobalamin 1 mg is given on alternate days until no further improvement is observed, as recommended by NICE guidance and the product information

The AHCA Preferred Drug List includes the same information as our Preferred Drug List, including any changes