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The genetic basis of major depression

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Although this form of thiamine deficiency, which we call gastrointestinal beriberi, is initially limited to the gastrointestinal system, it mostly progresses to systemic thiamine deficiency, often triggered by stresses of different etiologies

61 This unique cell death pattern, triggered by iron-dependent peroxidation of phospholipids, is governed by many cellular metabolic pathways, including the redox balance, mitochondrial function, amino acids metabolism, blood lipids, and glucose metabolism