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Enriched in di- and tripeptides, PH facilitates protein synthesis of the skeletal muscle via anabolism, leading to an increase in skeletal muscle mass 186 , 187

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The evolution of DDSs from passive carriers to intelligent, patient-centric platforms signifies promising progress in gout and hyperuricemia management, yet substantial challenges in clinical validation, scalability, and long-term safety persist, underscoring the need for sustained interdisciplinary efforts to fully realize their therapeutic potential