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Orforglipron, an oral small-molecule GLP-1 receptor agonist for obesity treatment

If this applies to you, mention your surgical history and discuss whether the medication interaction with your altered anatomy requires any special consideration in terms of absorption or side effect management

6 Positioning in guidelines In NICEs guideline on the management of type 2 diabetes in adults (NG28), SUs may be used first-line for rescue therapy in symptomatic hyperglycaemia, or if low cardiovascular risk and metformin intolerance/contraindication

Potentiation of GLP-1 action through receptor agonists has demonstrated efficacy in treating metabolic disease (61, 62)