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Glutathione is the body's primary antioxidant, neutralizing free radicals, recycling other antioxidants, and protecting cells from daily oxidative burden

Astrocytes generate an inductive tightening influence on the endothelium through the production of sonic hedgehog (Shh) (Alvarez et al., 2011) and basic fibroblast growth factor (bFGF) (Sobue et al., 1999) that assist in forming a restrictive BBB by promoting endothelial expression of tight junction (TJ) proteins, occludin, claudins, and zonula occludens (ZO)

Reduced L-Glutathione features the reduced form of glutathione, the most active form in the body

Biochimica Et Biophysica Acta (BBA) - General Subjects 1860(1):4656