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By dissecting the molecular switches that control airway inflammatory responses, oxidative damage, and structural remodeling, researchers are identifying novel therapeutic opportunities that may address the unmet needs in the management of severe and therapy-resistant asthma

GnRH analogues (e.g., goserelin [Zoladex], leuprorelin [Prostap]): These induce a temporary menopausal state and are associated with changes in body composition, including increased fat mass and reduced lean muscle mass

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The radiation cutoff time was established at 20 s to prevent potential tissue damage if the mouse did not respond