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There are other forms of bias in these datasets including channeling (e.g., the prescribing pattern depends on a patient characteristic (particularly diabetes or obesity) that is a PDAC risk factor), detection (e.g., overreporting due to additional testing to rule out a suspected adverse event (e.g., imaging triggered by pancreas enzyme elevations)), and Weber effect (initial increase in event reporting shortly after drug launch) 49

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[37] Furthermore, in another double-blind study, Berbevis at a dosage of 550 mg once daily showed similar benefits on blood lipids, blood sugar control, and body fat measurements, but researchers also showed an 11% decrease in the body fat to muscle mass ratio