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focused on patients with head and neck cancer, revealing no significant difference in the overall response rate, which represents the percentage of patients achieving complete or partial response, between the glutamine and placebo groups 10 weeks post-chemoradiotherapy completion [123]

Urology 77 , 313319 (2011)

This case illustrates a variant anaphylactoid reaction to intravenously administered acetylcysteine and emphasizes the need for practitioners to consider the potential for these reactions prior to initiation of therapy and indicates appropriate treatment of these reactions

NICE NG28 and the MHRA advise considering B12 monitoring in long-term metformin users who have symptoms or risk factors for deficiency, as metformin can impair B12 absorption in the terminal ileum