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a retrospective analysis of 28 patients

Breast Cancer Res Treat 2012;132(1):175187

Regarding the refinement for Chc-Apl2.1 we have included secondary structure restraints, NCS torsion restrains, TLS refinement (at the beginning of the refinement one per chain and after the initial cycles the different TLS groups were calculated using phenix), grouped Bfactor refinement using PHENIX (1.21_5207) 58,59