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2016;11(4):e0153727
Ongoing research aims to better understand optimal timing and dosage, aiming to maximize therapeutic effects while minimizing side effects
Thioether macrocycles targeting human Met ectodomain were selected using the RaPID system 13,39 , slightly modified as follows: 1 M mRNA library was incubated with 1.5 M puromycin linker in the presence of T4 RNA ligase for 30 min at 25 C and was purified by phenolchloroform extraction and ethanol precipitation
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