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Notwithstanding the lack of strong evidence linking Skin Whitening to these disorders

100-103 Laboratory research has shown licorice phytoestrogens bind estrogen receptor sites with no more than 1/1,000 th the affinity of E2 and with a preference for ER-beta, while other licorice compounds have anti-estrogenic effects

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To address sleep disturbances, melatonin is frequently employed