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Because B12 is water soluble, your body does not store it, so it needs to be replenished on a consistent basis

Incorporating vitamin B6 can help mitigate side effects such as nausea, stabilize mood, and support energy metabolism, while vitamin B12 is essential for preventing deficiencies, maintaining energy levels, and supporting neurological health

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The problem is that the tablets that doctors can currently prescribe in the UK are nowhere near 1mg in strength, I believe they are 50mcg and the suggested dosage is 50-150 mcg taken between meals so for 150mcg you would take 3 tablets