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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Recht J., Martinez A., Torello S., Kolter R

Research published in 2011 found that elderly subjects had markedly lower glutathione concentrations compared to younger adults, with 83% higher fractional synthesis rates in young people

In some embodiments, the otic formulation or composition comprises between about 0.1% to about 30% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof