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The effects of dutasteride 0.5 mg/day on semen characteristics were evaluated in normal male volunteers aged 18 to 52 (n = 27 dutasteride, n = 23 placebo) throughout 52 weeks of treatment and 24 weeks of post-treatment follow-up

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Costanzo G, Curatolo S, Bus B, et al

Pro-inflammatory cytokines like IL-1 and TNF- have been labeled as the major destructive compounds contributing to cartilage loss in the ECM, but MSM could exhibit protected effects on cartilage by suppressing the effects of IL-1 and TNF- 5, thereby preventing degradation