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A randomized controlled trial (RCT) demonstrated that after 6 months of supplementation with 1.2 g/d of EPA + DHA for patients with knee OA, the WOMAC pain score decreased by 23% ( p = 0.02), and the synovial inflammation assessed by MRI was relieved (42)

Pasalnya, penggunaannya secara berlebihan dapat meningkatkan risiko terjadinya iritasi, kemerahan, bahkan risiko ochronosis, yaitu perubahan warna kulit menjadi biru kehitaman

Notably, FoB persist in Gclc -deficient mice and are characterized by increased ROS and acquire characteristics of Gclc -sufficient MZB