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They possess a high synthetic capacity for GSH due to high expression of (GCL) and cystine/glutamate antiporter (xCT), and can export GSH to neighboring neurons and glia
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Furthermore, the authors pointed out a possible connection between Nr4a1 and Gpx1 transcription, indicating that the antioxidant properties of NAC may be partially mediated through the modulation of stress-responsive transcription factors
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