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This change incorporates the following estimates:6,387 hours for computer system analysts (2,129 submissions 3 hr/submission), 4,258 hours for medical and health service managers (2,129 submissions 2 hr/submission), 2,129 hours for LPNs (2,129 submissions 1 hr/submission), 2,129 hours for billing clerks (2,129 submissions 1 hr/submission), and 2,129 hours for physicians (2,129 submissions 1 hr/submission)

However, gastrointestinal effects like nausea and vomitingwhich involve similar nerve and muscle pathwaysare documented in 3040% of users, suggesting that some patients are more predisposed to digestive disturbances than others

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