Its role in the management of several important conditions like autism, cystic fibrosis, drug induced hepatic injury, HIV, and many others 1821,50 is just becoming apparent, but the main stumbling block for its therapeutic potential is the route of administration
For example, several inorganic nanomaterials, including metal chalcogenide nanoparticles, hybrid metal nanoparticles, and single-atom metal nanoparticles, can act as GSH peroxidase-mimicking nanozymes to exhaust intracellular GSH in cancer cells ( 2 O 2 , realizing tumor-specific catalytic therapy with response to the TME featuring overexpressed GSH and H 2 O 2 (Yin et al., 2019)
In Conclusion Melasma requires more than one product or treatment
L-arginine supplementation can lower blood pressure and should be used cautiously in individuals taking antihypertensive medications or those with existing hypotension