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Age, sex, and APOE 4 carrier status were included because they are well-established risk factors for AD

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The goal of these detoxification pathways is to create molecules that the body can easily get rid of (urine, feces, sweat).[ref] CYP450 Genetic Variants: Genetic variants in CYP450 enzymes can significantly impact how an individual metabolizes various toxicants, medications, and substances produced within the body

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