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When appetite decreases, overall food intake declines, and protein is typically the first macronutrient to be reduced

Swallow the tablet whole and dont cut, crush, or chew the tablet

As of 2024, in the UK, tirzepatide was rolled out more broadly under new obesity guidance, published by the National Institute for Health and Care Excellence (NICE), aligning it alongside established agents such as semaglutide 3

In a 30-week, randomized, open-label, controlled trial in adults with type 2 diabetes mellitus [see Adverse Reactions (6.1)], anti-exenatide antibody assessments were performed at baseline and at 4-week intervals from Week 6 to Week 30