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Emergency Preparedness : Ensure your provider carries emergency medications (epinephrine, antihistamines, corticosteroids) and has protocols for managing adverse reactions

Important class risks include gallbladder disease (cholelithiasis, cholecystitis) and, specifically for semaglutide in patients with type 2 diabetes, potential worsening of diabetic retinopathy complications in those with pre-existing retinopathy

POTS is not listed as a recognised adverse effect in the Summary of Product Characteristics (SmPC) for Wegovy, and no signal has been highlighted in publicly available regulatory documents from the MHRA or European Medicines Agency (EMA) to date

That lowers the barrier to testing it for alcohol dependence and increases the possibility of repurposing it for the treatment of alcohol use disorder